News & Events

Press Releases

April 8, 2021

Max Cooper: Evolution of Alternative Adaptive Immune Systems

Max Cooper, Georgia Research Alliance Eminent Scholar, Professor of Pathology and Laboratory Medicine, Emory University School of Medicine, delivered the 2021 Lasker-APSA Lecture at the annual meeting of the AAP/ASCI/APSA on April 8.

September 24, 2019

B and T cells—the organizing principle of the adaptive immune system

The 2019 Albert Lasker Basic Medical Research Award honors Max D. Cooper and Jacques Miller for discoveries that have launched the course of modern immunology.

January 2018

Max Cooper: Laureates of the Japan Prize

Dr. Max Cooper is named 2018 Japan Prize Laureate for his discovery of B and T lymphocyte lineages and its impact on understanding disease pathology and therapeutic development.

In The News

Nature | November 1, 2021

Refining the toolkit for sugar analysis

Antibodies and other reagents for glycans have lagged behind those for proteins and nucleic acids, but the field is catching up. This article in Nature features Max Cooper’s discoveries in this space and the work that powers NoVab.

Emory Medicine | Winter 2018

Learning from Lampreys An ancient immune system provides insights into our own

In immunologist Max Cooper’s Emory Vaccine Center lab, researchers see lampreys as windows into the distant past and biomedical treasure troves that may contain disease-fighting secrets from another eon.

January 29, 2015

Where Science and Commerce Intersect

NoVab leaders are highlighted in this article about the history of the Georgia Research Alliance, the mission of which is to expand research and commercialization capacity in Georgia’s universities in order to launch new companies, create high-value jobs and transform lives.

Therapeutics for plasma cell malignancies

NovAb is exploring the biology of primitive, jawless, fish-like lampreys and hagfish as a model for plasma cell-specific antibodies to treat plasma cell malignancies in humans.

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Publications

Adler M, Schulz S, Fischer R, Niemeyer CM. Detection of Rotavirus from stool samples using a standardized immuno-PCR (“Imperacer”) method with end-point and real-time detection. Biochem Biophys Res Commun. 2005;333(4):1289-94. Epub 2005/06/28. doi: 10.1016/j.bbrc.2005.06.027. PubMed PMID: 15979577.

Cooper MD, Alder MN. The evolution of adaptive immune systems. Cell. 2006;124(4):815-22. Epub 2006/02/25. doi: 10.1016/j.cell.2006.02.001. PubMed PMID: 16497590.

Collins BC, Gunn RJ, McKitrick TR, Cummings RD, Cooper MD, Herrin BR, Wilson IA. Structural Insights into VLR Fine Specificity for Blood Group Carbohydrates. Structure. 2017;25(11):1667-78 e4. Epub 2017/10/11. doi: 10.1016/j.str.2017.09.003. PubMed PMID: 28988747; PMCID: PMC5677568.

Cummings RD. The repertoire of glycan determinants in the human glycome. Mol Biosyst. 2009;5(10):1087-104. Epub 2009/09/17. doi: 10.1039/b907931a. PubMed PMID: 19756298.

Gunn RJ, Herrin BR, Acharya S, Cooper MD, Wilson IA. VLR Recognition of TLR5 Expands the Molecular Characterization of Protein Antigen Binding by Non-Ig-based Antibodies. J Mol Biol. 2018;430(9):1350-67. Epub 2018/03/30. doi: 10.1016/j.jmb.2018.03.016. PubMed PMID: 29596914; PMCID: PMC5915902.

Han BW, Herrin BR, Cooper MD, Wilson IA. Antigen recognition by variable lymphocyte receptors. Science. 2008;321(5897):1834-7. Epub 2008/09/27. doi: 10.1126/science.1162484. PubMed PMID: 18818359; PMCID: PMC2581502.

Herrin BR, Alder MN, Roux KH, Sina C, Ehrhardt GR, Boydston JA, Turnbough CL, Jr., Cooper MD. Structure and specificity of lamprey monoclonal antibodies. Proc Natl Acad Sci U S A. 2008;105(6):2040-5. Epub 2008/02/02. doi: 10.1073/pnas.0711619105. PubMed PMID: 18238899; PMCID: PMC2542867.

Herrin BR, Cooper MD. Alternative adaptive immunity in jawless vertebrates. J Immunol. 2010;185(3):1367-74. Epub 2010/07/28. doi: 10.4049/jimmunol.0903128. PubMed PMID: 20660361.

Chan JTH, Liu Y, Khan S, St-Germain JR, Zou C, Leung LYT, Yang J, Shi M, Grunebaum E, Campisi P, Propst EJ, Holler T, Bar-Or A, Wither JE, Cairo CW, Moran MF, Palazzo AF, Cooper MD, Ehrhardt GRA. A tyrosine sulfation-dependent HLA-I modification identifies memory B cells and plasma cells. Sci Adv. 2018;4(11):eaar7653.
Epub 2018/11/13. doi: 10.1126/sciadv.aar7653. PubMed PMID: 30417091; PMCID: PMC6221509.